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NIH - National Institutes of Health National Cancer Institute Division of Cancer Treatment and Diagnosis Center for Cancer Research
NCI Experimental Therapeutics Program (NExT)
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Last Updated: 09/18/18

Preclinical Development Stage NExT Projects

Applicant Institute Project
Brown, Bob Dicerna Pharmaceuticals, Inc. β-catenin/CTNNB1 DsiRNA LNP Therapeutic for HCC and CRC
Cassady, Kevin University of Alabama at Birmingham Production of Clinical Grade Oncolytic HSV C134 for Phase 1 Clinical Trial
Markowitz, Sanford Case Western Reserve University SW033291 Markedly Accelerates Tri-Lineage Recovery After Marrow Transplant
Perera, Liyanage National Cancer Institute, Center for Cancer Research, NIH CARs targeting the chemokine receptor CCR4 as a therapeutic modality for T-cell leukemias
Rittenhouse-Olson, Kate For-Robin, Inc hJAA-F11, a Humanized Anti-Thomsen Friedenreich Antibody for Cancer Therapy
Roden, Richard Johns Hopkins University Production of an HPV16 L2E6E7 vaccine with GPI-0100 adjuvant for the treatment of HPV-associated disease
Rosenthal, Eben University of Alabama Birmingham Intraoperative Optical Imaging to Guide Surgical Resection of Cancer
Schnitzer, Jan Proteogenomics Research Institute for Systems Medicine Developing hAnnA1-based immunoconjugates for cancer detection and treatment